Jonathan Golledge Selected Research

Angiotensin II

3/2024	Systematic Review Examining the Association Between Angiotensin Converting Enzyme Inhibitor or Angiotensin Receptor Blocker Prescription and Abdominal Aortic Aneurysm Growth and Events.
3/2024	The Potential Involvement of Glycocalyx Disruption in Abdominal Aortic Aneurysm Pathogenesis.
11/2023	Effect of Hydralazine on Angiotensin II-Induced Abdominal Aortic Aneurysm in Apolipoprotein E-Deficient Mice.
2/2023	Moxonidine Increases Uptake of Oxidised Low-Density Lipoprotein in Cultured Vascular Smooth Muscle Cells and Inhibits Atherosclerosis in Apolipoprotein E-Deficient Mice.
1/2021	Parallel Murine and Human Aortic Wall Genomics Reveals Metabolic Reprogramming as Key Driver of Abdominal Aortic Aneurysm Progression.
1/2020	Vitamin D deficiency promotes large rupture-prone abdominal aortic aneurysms and cholecalciferol supplementation limits progression of aneurysms in a mouse model.
11/2019	Depletion of CD11c+ dendritic cells in apolipoprotein E-deficient mice limits angiotensin II-induced abdominal aortic aneurysm formation and growth.
10/2018	A diet enriched with tree nuts reduces severity of atherosclerosis but not abdominal aneurysm in angiotensin II-infused apolipoprotein E deficient mice.
1/2018	Diabetes Reduces Severity of Aortic Aneurysms Depending on the Presence of Cell Division Autoantigen 1 (CDA1).
6/2017	High serum thrombospondin-1 concentration is associated with slower abdominal aortic aneurysm growth and deficiency of thrombospondin-1 promotes angiotensin II induced aortic aneurysm in mice.

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Jonathan Golledge Research Topics

Disease

101	Abdominal Aortic Aneurysm 03/2024 - 06/2005
35	Stroke (Strokes) 04/2024 - 02/2002
32	Peripheral Arterial Disease 06/2023 - 08/2006
30	Atherosclerosis 01/2024 - 07/2004
28	Myocardial Infarction 12/2023 - 02/2008
27	Inflammation (Inflammations) 01/2023 - 12/2006
23	Aneurysm (Aneurysms) 03/2024 - 06/2005
21	Cardiovascular Diseases (Cardiovascular Disease) 01/2023 - 05/2008
20	Rupture 03/2024 - 11/2009
19	Hypertension (High Blood Pressure) 04/2023 - 01/2007
16	Aortic Aneurysm (Aneurysm, Aortic) 01/2021 - 03/2007
14	Thrombosis (Thrombus) 01/2023 - 09/2008
12	Foot Diseases 11/2023 - 08/2020
12	Intermittent Claudication 01/2022 - 01/2007
11	Atherosclerotic Plaque (Atheroma) 01/2022 - 05/2007
7	Ischemic Stroke 04/2024 - 04/2014
7	Coronary Disease (Coronary Heart Disease) 01/2024 - 02/2008
7	Neoplasms (Cancer) 10/2023 - 01/2014
6	Foot Ulcer 07/2023 - 01/2016
6	Infections 01/2023 - 10/2015
6	Carotid Artery Diseases 07/2022 - 07/2004
6	Vascular Diseases (Vascular Disease) 07/2013 - 08/2007
5	Wounds and Injuries (Trauma) 01/2023 - 10/2015
5	Ischemia 01/2023 - 05/2013
4	Lung Neoplasms (Lung Cancer) 10/2023 - 01/2014
4	Necrosis 08/2023 - 07/2014
4	Ulcer 07/2023 - 01/2016
4	Type 2 Diabetes Mellitus (MODY) 01/2021 - 11/2014
4	Heart Failure 11/2020 - 03/2012
4	Dyslipidemias (Dyslipidemia) 10/2018 - 05/2010
4	Aortic Rupture 01/2018 - 12/2014
4	Vascular Calcification 01/2011 - 03/2008
3	Carotid Stenosis (Carotid Artery Stenosis) 04/2024 - 07/2022
3	Body Weight (Weight, Body) 11/2023 - 07/2014
3	Syncope (Fainting) 10/2023 - 07/2016
3	Coronary Artery Disease (Coronary Atherosclerosis) 08/2023 - 07/2013
3	Obesity 01/2023 - 01/2007
3	Transient Ischemic Attack 07/2022 - 01/2022
3	Pain (Aches) 01/2022 - 10/2008
3	Frailty 01/2022 - 03/2021

Drug/Important Bio-Agent (IBA)

33	Angiotensin IIIBA 03/2024 - 07/2004
23	Biomarkers (Surrogate Marker)IBA 01/2024 - 08/2007
21	ApolipoproteinsIBA 11/2023 - 07/2009
15	LipidsIBA 02/2023 - 01/2007
13	Proteins (Proteins, Gene)FDA Link 04/2024 - 07/2004
13	omega-Chloroacetophenone (Mace)IBA 04/2023 - 05/2008
13	Apolipoproteins E (ApoE)IBA 02/2023 - 04/2010
12	CytokinesIBA 01/2022 - 06/2005
11	OsteoprotegerinIBA 01/2018 - 07/2004
10	diformyl dapsone (DFD)IBA 11/2023 - 08/2020
10	HomocysteineIBA 03/2021 - 02/2008
9	Matrix Metalloproteinases (MMPs)IBA 01/2020 - 06/2005
8	OsteopontinIBA 01/2020 - 07/2004
8	Fenofibrate (CiL)FDA LinkGeneric 01/2020 - 05/2007
7	Testosterone (Sustanon)FDA Link 03/2021 - 03/2010
7	C-Reactive ProteinIBA 03/2021 - 01/2007
6	MicroRNAs (MicroRNA)IBA 11/2023 - 06/2014
6	Hydroxymethylglutaryl-CoA Reductase Inhibitors (HMG-CoA Reductase Inhibitors)IBA 04/2023 - 12/2006
6	Matrix Metalloproteinase 9 (Gelatinase B)IBA 11/2022 - 07/2014
6	Telmisartan (Micardis)FDA Link 10/2022 - 06/2015
6	Peptides (Polypeptides)IBA 01/2021 - 09/2011
6	Peroxisome Proliferator-Activated Receptors (PPAR)IBA 01/2020 - 05/2007
6	Gonadal Steroid Hormones (Sex Hormones)IBA 01/2020 - 03/2011
6	LigandsIBA 01/2019 - 05/2007
5	oxidized low density lipoproteinIBA 02/2023 - 01/2008
5	Scarlet Red (Sudan IV)IBA 02/2023 - 12/2010
5	CholesterolIBA 11/2021 - 03/2008
5	Antihypertensive Agents (Antihypertensives)IBA 11/2020 - 07/2014
5	Estradiol (Delestrogen)FDA LinkGeneric 01/2017 - 11/2013
4	Angiotensin Receptor AntagonistsIBA 03/2024 - 06/2015
4	Glucose (Dextrose)FDA LinkGeneric 11/2023 - 11/2014
4	LDL CholesterolIBA 07/2022 - 12/2019
4	Reactive Oxygen Species (Oxygen Radicals)IBA 01/2021 - 09/2011
4	OsteocalcinIBA 01/2021 - 05/2010
4	CreatinineIBA 01/2018 - 09/2009
4	Transforming Growth Factor beta (TGF-beta)IBA 01/2018 - 04/2010
4	Thyroxine (Levothyroxine)FDA LinkGeneric 01/2018 - 10/2013
4	fibrin fragment D (D-dimer)IBA 01/2018 - 02/2011
4	Dihydrotestosterone (Androstanolone)IBA 01/2017 - 11/2013
4	Phenobarbital (Luminal)FDA Link 02/2012 - 05/2008
3	Angiotensin-Converting Enzyme Inhibitors (ACE Inhibitors)IBA 03/2024 - 01/2021
3	Hydralazine (Apresoline)FDA LinkGeneric 11/2023 - 11/2020
3	SaltsIBA 01/2023 - 02/2013
3	Angiopoietin-1IBA 11/2022 - 04/2014
3	AngiotensinsIBA 10/2022 - 01/2019
3	Metformin (Glucophage)FDA LinkGeneric 12/2021 - 01/2019
3	Uric Acid (Urate)IBA 11/2021 - 12/2017
3	Vitamin D FDA LinkGeneric 03/2021 - 01/2014
3	KininsIBA 01/2021 - 01/2016
3	Pancreatic Elastase (Elastase)IBA 01/2021 - 12/2014
3	AdipokinesIBA 01/2021 - 01/2007
3	AndrogensIBA 01/2020 - 11/2013
3	Matrix Metalloproteinase 2 (Gelatinase A)IBA 01/2020 - 12/2014

Therapy/Procedure

28	Therapeutics 04/2024 - 09/2007
16	Surgical Amputation (Amputations) 12/2023 - 11/2008
13	Drug Therapy (Chemotherapy) 11/2023 - 12/2010
7	Carotid Endarterectomy 10/2023 - 05/2007
4	Vascular Surgical Procedures 02/2024 - 01/2019
4	Subcutaneous Infusions 01/2017 - 07/2009
3	Secondary Prevention 08/2023 - 05/2022